Lavado Nasal Rhinodocuhe
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Aval Científico

  • Jiao J, Yang J, Li Y, Zhang L. Hypertonic saline and seawater solutions damage sinonasal epithelial cell air‐liquid interface cultures. International Forum of Allergy; Rhinology. 2019;10(1):59-68.
  • Sauvalle, M. and Alvo, A., 2018. Effect of the temperature of nasal lavages on mucociliary clearance: a randomised controlled trial. European Archives of Oto-Rhino-Laryngology, 275(9), pp.2403-2406.
  • Piromchai, P., Kasemsiri, Laohasiriwong and Thanaviratananich, 2013. Chronic rhinosinusitis and emerging treatment options. International Journal of General Medicine, p.453.
  • Sindwani, R., 2010. Impact of isotonic and hypertonic saline solutions on mucociliary activity in various nasal pathologies: clinical study. Yearbook of Otolaryngology-Head and Neck Surgery, 2010, pp.205-206.
  • Hauptman, G. and Ryan, M., 2007. The effect of saline solutions on nasal patency and mucociliary clearance in rhinosinusitis patients. Otolaryngology–Head and Neck Surgery, 137(5), pp.815-821.
  • Cohen, N., 2006. Sinonasal Mucociliary Clearance in Health and Disease. Annals of Otology, Rhinology; Laryngology, 115(9), pp.20-26
  • Boek, W., Graamans, K., Natzijl, H., van Rijk, P. and Huizing, E., 2002. Nasal Mucociliary Transport: New Evidence for a Key Role of Ciliary Beat Frequency. The Laryngoscope, 112(3), pp.570-573.
  • Caroline Feliz Fonseca Sepeda da Silva, et al. Symptom assessment after nasal irrigation with xylitol in the postoperative period of endonasal endoscopic surgery. Brazilian Journal of Otorhinolaryngology. 2022;88(2):243-250.
  • Hui N, Yii N, Robinson D. Xylitol nasal preparations in sinonasal disease: a literature review and meta-analysis. Aust J Otolaryngol 2022;5:8.
  • Kim DH, Kim Y, Lim IG, et al. Effect of Postoperative Xylitol Nasal Irrigation on Patients with Sinonasal Diseases. Otolaryngology–Head and Neck Surgery. 2019;160(3):550-555.
  • de Paiva Leite S, Douglas R. How does sinus surgery affect topical irrigation distribution?. Current Opinion in Otolaryngology Head; Neck Surgery. 2018;26(1):21-26.
  • Giotakis A, Karow E, Scheithauer M, Weber R, Riechelmann H. Saline irrigations following sinus surgery a controlled, single blinded, randomized trial. Rhinology journal. 2016;54(4):302-310.
  • Low T, Woods C, Ullah S, Carney A. A Double-Blind Randomized Controlled Trial of Normal Saline, Lactated Ringer’s, and Hypertonic Saline Nasal Irrigation Solution after Endoscopic Sinus Surgery. American Journal of Rhinology; Allergy. 2014;28(3):225-231.
  • Kim S, Sung U, Jung J, Paik J, Woo J, Cha H et al. The Effect of Maxillary Sinus Irrigation on Early Prognostic Factors after Endoscopic Sinus Surgery: A Preliminary Study. American Journal of Rhinology; Allergy. 2013;27(5):e158-e161.
  • Rudmik L, Soler Z, Orlandi R, Stewart M, Bhattacharyya N, Kennedy D et al. Early postoperative care following endoscopic sinus surgery: an evidence-based review with recommendations. International Forum of Allergy & Rhinology.
  • Harvey R, Snidvongs K, Kalish L, Oakley G, Sacks R. Corticosteroid nasal irrigations are more effective than simple sprays in a randomized double-blinded placebo-controlled trial for chronic rhinosinusitis after sinus surgery. International Forum of Allergy; Rhinology. 2018;8(4):461-470.
  • Tugrul S, Dogan R, Eren S, Meric A, Ozturan O. The use of large volume low pressure nasal saline with fluticasone propionate for the treatment of pediatric acute rhinosinusitis. International Journal of Pediatric Otorhinolaryngology. 2014;78(8):1393-1399.
  • Liang J, Lane A.Topical Drug Delivery for Chronic Rhinosinusitis. Current Otorhinolaryngology Reports. 2012;1(1):51-60.
  • Baxter AL, Schwartz KR, Johnson RW, et al. Rapid initiation of nasal saline irrigation to reduce severity in high-risk COVID+ outpatients. Ear Nose Throat J. 2022
  • Radulesco T, Lechien JR, et al. Safety and Impact of Nasal Lavages During Viral Infections Such as SARS-CoV-2. Ear Nose Throat J. 2021 Apr;100(2_suppl):188S-191S. 
  • Singh S, Aggarwal P, Ravichandiran V. Immunological Response of the Respiratory Tract in the SARS-CoV-2 Infection. Coronaviruses. 2021;2(9).
  • Farrell N, Klatt-Cromwell C, Schneider J. Benefits and Safety of Nasal Saline Irrigations in a Pandemic—Washing COVID-19 Away. JAMA Otolaryngology–Head; Neck Surgery. 2020;146(9):787.
  • Ramalingam S, Graham C, Dove J, Morrice L, Sheikh A. Hypertonic saline nasal irrigation and gargling should be considered as a treatment option for COVID-19. Journal of Global Health. 2020;10(1).
  • Ramalingam S, Graham C, Dove J, Morrice L, Sheikh A. A pilot, open labelled, randomised controlled trial of hypertonic saline nasal irrigation and gargling for the common cold. Scientific Reports. 2019;9(1).
  • Piromchai P et al. Squeeze bottle versus syringe nasal saline irrigation for persistent allergic rhinitis – a randomized controlled trial. Rhinology 2020; 58(5):460-464.
  • Gabory L, Kérimian M, Baux Y, Boisson N, Bordenave L. Computational fluid dynamics simulation to compare large volume irrigation and continuous spraying during nasal irrigation. International Forum of Allergy; Rhinology. 2019;10(1):41-48.
  • Piromchai P, Puvatanond C, Kirtsreesakul V, Chaiyasate S, Thanaviratananich S. Effectiveness of nasal irrigation devices: a Thai multicentre survey. PeerJ. 2019;7:e7000.
  • Snidvongs K, Thanaviratananich S. Update on Intranasal Medications in Rhinosinusitis. Current Allergy and Asthma Reports. 2017;17(7).
  • Campos J, Heppt W, Weber R. Nasal douches for diseases of the nose and the paranasal sinuses—a comparative in vitro investigation. European Archives of Oto-Rhino-Laryngology. 2013;270(11):2891-2899.
  • Sindwani R. Nasal saline for chronic sinonasal symptoms: a randomized controlled trial. Yearbook of Otolaryngology-Head and Neck Surgery. 2008;2008:209-210.
  • Wormald P, Cain T, Oates L, Hawke L, Wong I. A Comparative Study of Three Methods of Nasal Irrigation. The Laryngoscope. 2004;114(12):2224-2227.
  • Jung M, Lee JY, Ryu G, Lee KE, Hong SD, Choi J, Kim S, Ahn K, Dhong HJ, Chung SK, Kim J, Kim HY. Beneficial effect of nasal saline irrigation in children with allergic rhinitis and asthma: A randomized clinical trial. Asian Pac J Allergy Immunol. 2020 Dec;38(4):251-257.
  • Chandy Z, Ference E, Lee J. Clinical Guidelines on Chronic Rhinosinusitis in Children. Current Allergy and Asthma Reports. 2019;19(2).
  • Ragab A, Farahat T, Al-Hendawy G, Samaka R, Ragab S, El-Ghobashy A. Nasal saline irrigation with or without systemic antibiotics in treatment of children with acute rhinosinusitis. International Journal of Pediatric Otorhinolaryngology. 2015;79(12):2178-2186.
  • Pham V, Sykes K, Wei J. Long-term outcome of once daily nasal irrigation for the treatment of pediatric chronic rhinosinusitis. The Laryngoscope. 2013;124(4):1000-1007.
  • Jeffe J, Bhushan B, Schroeder J. Nasal saline irrigation in children: A study of compliance and tolerance. International Journal of Pediatric Otorhinolaryngology. 2012;76(3):409-413.
  • Wei J, Sykes K, Johnson P, He J, Mayo M. Safety and efficacy of once-daily nasal irrigation for the treatment of pediatric chronic rhinosinusitis. The Laryngoscope. 2011;121(9):1989-2000.
  • Jung M, Lee JY, Ryu G, Lee KE, Hong SD, Choi J, Kim S, Ahn K, Dhong HJ, Chung SK, Kim J, Kim HY. Beneficial effect of nasal saline irrigation in children with allergic rhinitis and asthma: A randomized clinical trial. Asian Pac J Allergy Immunol. 2020 Dec;38(4):251-257.
  • Head K, Snidvongs K, Glew S, Scadding G, Schilder A, Philpott C et al. Saline irrigation for allergic rhinitis. Cochrane Database of Systematic Reviews. 2017.
  • Nguyen S, Psaltis A, Schlosser R. Isotonic Saline Nasal Irrigation is an Effective Adjunctive Therapy to Intranasal Corticosteroid Spray in Allergic Rhinitis. American Journal of Rhinology; Allergy. 2014;28(4):308-311.
  • Chandy Z, Ference E, Lee J. Clinical Guidelines on Chronic Rhinosinusitis in Children. Current Allergy and Asthma Reports. 2019;19(2).
  • Hopkins C. Chronic Rhinosinusitis with Nasal Polyps. New England Journal of Medicine. 2019;381(1):55-63.
  • Zakrzewska A. Diagnosis and treatment of Chronic Rhinosinusitis in Children according European Position Paper on Rhinosinusitis and nasal Polyps –EPOS-2012 and American Academy Otolaryngology-Head and Neck Surgery 2014. Polski Przegląd Otorynolaryngologiczny. 2018;7(2):27-32.
  • Rudmik L, Soler Z. Medical Therapies for Adult Chronic Sinusitis. JAMA. 2015;314(9):926.
  • Ragab A, Farahat T, Al-Hendawy G, Samaka R, Ragab S, El-Ghobashy A. Nasal saline irrigation with or without systemic antibiotics in treatment of children with acute rhinosinusitis. International Journal of Pediatric Otorhinolaryngology. 2015;79(12):2178-2186.
  • Pham V, Sykes K, Wei J. Long-term outcome of once daily nasal irrigation for the treatment of pediatric chronic rhinosinusitis. The Laryngoscope. 2013;124(4):1000-1007.
  • Wei J, Sykes K, Johnson P, He J, Mayo M. Safety and efficacy of once-daily nasal irrigation for the treatment of pediatric chronic rhinosinusitis. The Laryngoscope. 2011;121(9):1989-2000.
  • Rosenfeld R. Clinical Practice Guideline on Adult Sinusitis. Otolaryngology–Head and Neck Surgery. 2007;137(3):365-377.
  • Scadding G, Durham S, Mirakian R, Jones N, Drake-Lee A, Ryan D et al. BSACI guidelines for the management of rhinosinusitis and nasal polyposis. Clinical; Experimental Allergy. 2007;38(2):260-275.
  • Caroline Feliz Fonseca Sepeda da Silva, et al.Symptom assessment after nasal irrigation with xylitol in the postoperative period of endonasal endoscopic surgery. Brazilian Journal of Otorhinolaryngology. 2022;88(2):243-250.
  • Hui N, Yii N, Robinson D. Xylitol nasal preparations in sinonasal disease: a literature review and meta-analysis. Aust J Otolaryngol 2022;5:8.
  • Lin L, Tang X, Wei J, Dai F, Sun G. Xylitol nasal irrigation in the treatment of chronic rhinosinusitis. American Journal of Otolaryngology. 2017;38(4):383-389.
  • Weissman J, Fernandez F, Hwang P. Xylitol nasal irrigation in the management of chronic rhinosinusitis: A pilot study. The Laryngoscope. 2011;121(11):2468-2472.
  • Kontiokari T. Antiadhesive effects of xylitol on otopathogenic bacteria. Journal of Antimicrobial Chemotherapy. 1998;41(5):563-565.